Ha Thi’s work lies at the intersection between life science and business. He started 4 health and biotech companies and consults leading venture capital companies and innnovation hubs across the world to build better health solutions. The health tech and biotech startups he has helped to launch have a combined valuation of over 800 Mio. USD. Ha Thi received his PhD in Neuroscience and Molecular Biology from the world-renowned MRC Molecular Biological Laboratory at University of Cambridge, UK. At Cambridge, his discoveries created the foundation for major pharmaceutical drug discovery pipelines. Ha Thi is also a licensed medical doctor, having obtained his MD from Free University of Berlin. He was a scholar at Yale University and research fellow at Harvard Medical School and the Broad Institute at Massachusetts Institute ot Technology (MIT). Ha Thi is the recipient of numerous prestigious national and international scholarships and awards.
Research
After more than 10 years of research in the field of neurodegenerative and neurodevelopmental diseases, my research focus has recently shifted towards understanding and improving mental wellbeing at the individual and organizational level in Southeast Asia. Mental health burden is rampant in Southeast Asia, and the shortage of qualified counsellors necessitates the development of scalable on-demand interventions for improving mental helath. My research team and I are developing effective, scalable digital and peer-to-peer solutions for Southeast Asian Youth for the detection and improvement of mental health problems such as depression and anxiety. I am further interested in developing cultural adaptation frameworks to translate and localize modern "western" therapeutic concepts into the Southeast Asian context. Conversely, I am interested in researching traditional plant medicine and natural products that can be harnessed for improving mental health. I am always excited to work with driven students and enagage in innovative research collaborations.
So get in touch!
Specific Projects:
1. Developing & testing single interventions depression and anxiety in Vietnam & Southeast Asian Youth
2. Traditional medicine and natural products for mental health
Google Scholar: https://scholar.google.co.uk/citations?user=KchoWwEAAAAJ&hl=en
List of Publications
1. In vitro reconstitution of a highly processive recombinant human dynein complex
MA Schlager*, HT Hoang*, L Urnavicius, SL Bullock, AP Carter
The EMBO journal 33 (17), 1855-1868 340 2014
2. DYNC1H1 mutations associated with neurological diseases compromise processivity of dynein–dynactin–cargo adaptor complexes (*co-first author)
HT Hoang, MA Schlager, AP Carter, SL Bullock
Proceedings of the National Academy of Sciences 114 (9), E1597-E1606 106 2017
3. RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPs
Mark A McClintock, Carly I Dix, Christopher M Johnson, Stephen H McLaughlin, Rory J Maizels, Ha Thi Hoang, Simon L Bullock
Elife 7, e36312 85 2018
4. Lissencephaly-1 is a context-dependent regulator of the human dynein complex
Janina Baumbach, Andal Murthy, Mark A McClintock, Carly I Dix, Ruta Zalyte, Ha Thi Hoang, Simon L Bullock
Elife 6, e21768 79 2017
5. The role of chromogranin B in an animal model of multiple sclerosis
M Mo, HT Hoang, S Schmidt, RB Clark, BE Ehrlich
Molecular and Cellular Neuroscience 56, 102-114
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